Differential effects of low or high-fat dairy and fat derived from dairy products on MASLD
MASLD is related to nutrition, but evidence of an association between high-fat and low-fat dairy products is lacking, therefore, we evaluated this association by performing experimental studies in mice and an observational human study. For MASLD prevention, a differential effect based on the type of dairy products should be considered: low-medium fat low-sugar dairy products were found to be protective, in contrast high-fat dairy and generally high-fat diets may be harmful. It would be advisable to prefer low-fat low-sugar dairy products and minimise intake of high-fat dairy products; however, additional evidence is needed to allow generalisability of our findings.
Authors
- Revital Kariv (ORCID: https://orcid.org/0000-0002-3831-9020)
- Shira Zelber‐Sagi (ORCID: https://orcid.org/0000-0002-1324-7497)
- Oren Tirosh (ORCID: https://orcid.org/0000-0001-5407-0440)
- Oren Shibolet (ORCID: https://orcid.org/0000-0003-0081-3872)
- Dana Ivancovsky‐Wajcman (ORCID: https://orcid.org/0000-0002-6238-3938)
- Laura Sol Grinshpan (ORCID: https://orcid.org/0009-0003-7334-5739)
- Naomi Fliss‐Isakov (ORCID: https://orcid.org/0000-0003-4849-0291)
- Michal Verman
- Muriel Webb
Institutions
- Tel Aviv University (IL)
- Hebrew University of Jerusalem (IL)
- University of Haifa (IL)
Publication Details
- Journal
- JHEP Reports
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.jhepr.2024.101194
- Citations
- 5
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Ministry of Health, State of Israel