Elevated Troponin T in Immune-Checkpoint Inhibitor Myositis
A patient with metastatic renal cell carcinoma on axitinib and pembrolizumab had elevated high-sensitivity cardiac troponin T and normal high-sensitivity cardiac troponin I with unremarkable cardiac investigations. A noncardiac cause (myositis) was the likely cause for cardiac troponin T elevation. Cardiac troponin I may be a more appropriate marker to support a myocarditis diagnosis with concurrent myositis.
Authors
- Naveen S. Basappa (ORCID: https://orcid.org/0000-0002-3163-9902)
- Kai Yi Wu (ORCID: https://orcid.org/0000-0001-6546-2191)
- Carrie Ye (ORCID: https://orcid.org/0000-0002-9858-5398)
- Gábor Gyenes (ORCID: https://orcid.org/0000-0002-1177-3784)
- Carissa Beaulieu (ORCID: https://orcid.org/0000-0002-0007-8348)
- Sheri L. Koshman (ORCID: https://orcid.org/0000-0001-9867-051X)
- Albert K.Y. Tsui (ORCID: https://orcid.org/0000-0003-4200-1434)
- Anna K. Füzéry
- Joshua E. Raizman
Institutions
- University of Alberta (CA)
- Provincial Laboratory of Public Health (CA)
- Alberta Cancer Foundation (CA)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1016/j.jaccas.2024.102462
- Citations
- 2
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.77