Impact of SARS-CoV-2 vaccination in patients with vascular liver diseases: Observations from a VALDIG multicenter study
Patients with vascular liver disease (VLD) are at increased risk of both SARS-CoV-2 infection and severe COVID-19 disease. The potential risks associated with vaccination against this infection need thorough investigation. Our research enhances the understanding of the effects of COVID-19 vaccination in patients with VLD, highlighting its good tolerability. Moreover, patients with VLD appear to have a preserved immune response to SARS-CoV-2 vaccination, providing protection against severe COVID-19 infection. Our study cannot definitively establish a direct link between vaccination and thrombotic events, and no cases of vaccine-induced thrombocytopenia were reported.
Authors
- Juan Carlos García‐Pagán (ORCID: https://orcid.org/0000-0001-9032-4954)
- Aurélie Plessier (ORCID: https://orcid.org/0000-0001-5656-1622)
- Maria Cristina Morelli (ORCID: https://orcid.org/0000-0002-9742-1981)
- Xavier Verhelst (ORCID: https://orcid.org/0000-0002-2798-5415)
- Lara Orts (ORCID: https://orcid.org/0000-0002-3070-0310)
- Luis Ibáñez (ORCID: https://orcid.org/0000-0002-0309-2727)
- Ángela Puente (ORCID: https://orcid.org/0000-0002-8533-2412)
- Julian Schulze zur Wiesch (ORCID: https://orcid.org/0000-0002-5033-1938)
- Jonel Trebicka (ORCID: https://orcid.org/0000-0002-7028-3881)
- Eleanor Barnes (ORCID: https://orcid.org/0000-0002-0860-0831)
- Anna Baiges (ORCID: https://orcid.org/0000-0002-6963-9203)
- Edilmar Alvarado‐Tápias (ORCID: https://orcid.org/0000-0003-2036-6133)
- Thomas Marjot (ORCID: https://orcid.org/0000-0002-6542-6323)
- Carlos González‐Alayón (ORCID: https://orcid.org/0000-0003-0215-4874)
- Valeria Pérez‐Campuzano (ORCID: https://orcid.org/0000-0002-5997-9511)
- Pierre‐Emmanuel Rautou (ORCID: https://orcid.org/0000-0001-9567-1859)
- Elba Llop (ORCID: https://orcid.org/0000-0002-6612-7501)
- Macarena Simón‐Talero (ORCID: https://orcid.org/0000-0002-1409-3936)
- Michael Praktiknjo (ORCID: https://orcid.org/0000-0001-7033-9956)
- Georgina Meacham
- Laura Turco (ORCID: https://orcid.org/0000-0001-8148-3769)
- Luís Téllez (ORCID: https://orcid.org/0000-0002-9254-3891)
- Càndid Villanueva (ORCID: https://orcid.org/0000-0002-3674-914X)
- Virginia Hernández–Gea (ORCID: https://orcid.org/0000-0001-7937-984X)
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- G Grassi (ORCID: https://orcid.org/0000-0001-9182-8759)
- Payance Audrey
- Johanna Birte Bergmann
- Sam Murray
- Carmen Álvarez‐Navascués (ORCID: https://orcid.org/0000-0002-9496-2133)
- Marc Luetgehetmann
Institutions
- Inserm (FR)
- Universität Hamburg (DE)
- Université Paris Cité (FR)
- University of Münster (DE)
- University Hospital Bonn (DE)
- Hôpital Beaujon (FR)
- Hospital Universitario de Canarias (ES)
- Ghent University Hospital (BE)
- Hospital de Sant Pau (ES)
- Hospital General Universitario Gregorio Marañón (ES)
- University of Oxford (GB)
- Assistance Publique – Hôpitaux de Paris (FR)
- Marqués de Valdecilla University Hospital (ES)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- University Medical Center Hamburg-Eppendorf (DE)
- German Center for Infection Research (DE)
- Azienda USL di Bologna (IT)
- Vall d'Hebron Hospital Universitari (ES)
- Centre de Recherche sur l'Inflammation (FR)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- Hospital Universitario Central de Asturias (ES)
- Hospital Universitario Ramón y Cajal (ES)
- Medical University of Vienna (AT)
Publication Details
- Journal
- JHEP Reports
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.jhepr.2024.101191
- Citations
- 1
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.37