Inhibiting miRNA-146a suppresses mouse gallstone formation by regulating LXR/megalin/cubilin-media cholesterol absorption
The data demonstrates that miR-146 modulates gallbladder cholesterol absorption by targeting megalin, and prevents the pathogenesis of cholesterol gallstones.
Authors
- Shuangyan Wu (ORCID: https://orcid.org/0000-0003-0892-3072)
- Pingli Cao (ORCID: https://orcid.org/0000-0002-3984-963X)
- Bin Yang (ORCID: https://orcid.org/0000-0002-4244-1635)
- Guoqing Bao (ORCID: https://orcid.org/0000-0002-1685-1980)
- Weihong Chen (ORCID: https://orcid.org/0000-0001-8689-7311)
- Ding Luo (ORCID: https://orcid.org/0009-0009-3428-819X)
- Pinduan Bi
- Ming Wu
Institutions
- Kunming Medical University (CN)
- First Affiliated Hospital of Kunming Medical University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e36679
- Citations
- 3
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Natural Science Foundation of China
- Kunming Medical University