Challenges in the approach to a patient with aortic stenosis and cardiac amyloidosis with ATTR mutation associated with negative scintigraphy - A case report
Various diagnostic algorithms emphasize the use of myocardial scintigraphy for suspected CA-TTR. Genetic testing is crucial when scintigraphy results are negative, but clinical suspicion remains high, potentially circumventing invasive procedures. Compared with medical management alone, TAVI has been shown to improve quality of life and survival in patients with concurrent severe AS and CA.
Authors
- Luiz Felipe Camillis
- Helena Cramer Veiga Rey (ORCID: https://orcid.org/0000-0003-3920-5815)
- Adriana Soares Xavier de Brito (ORCID: https://orcid.org/0000-0002-9310-3580)
- Gabriel Camargo (ORCID: https://orcid.org/0000-0001-5203-6097)
- Clara Weksler (ORCID: https://orcid.org/0000-0001-9991-3739)
- Beny Binensztok
- Luciana Coutinho Bezerra
- Gabriela Carvalho Monnerat Magalhães
- Maysa Ramos Vilela
- Ellen Fernanda das Neves Braga
Publication Details
- Journal
- American Heart Journal Plus Cardiology Research and Practice
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.ahjo.2024.100444
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer