From pure testicular Teratoma to primitive neuroectodermal tumor: Successful management of Teratoma malignant transformation with widespread metastases in a young adult

Midline retroperitoneal masses in young males often present a diagnostic challenge, with metastases from testicular origins being a primary consideration. Beyond the initial pathology of testicular cancer, these masses can undergo transformation, including the development of teratomas. This report describes an unusual case of a calcified retroperitoneal mass originating from a testicular pure teratoma that underwent a rare transformation into a Primitive Neuroectodermal Tumor (PNET), comprising approximately 85 % of the tumor volume. The patient's successful treatment involved a comprehensive approach combining surgical resection and chemotherapy.

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Publication Details

Journal
Urology Case Reports
Published
2024-08-23
DOI
https://doi.org/10.1016/j.eucr.2024.102830
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
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article

From pure testicular Teratoma to primitive neuroectodermal tumor: Successful management of Teratoma malignant transformation with widespread metastases in a young adult

Amir Alinejad Khorram, Navid Masoumi, Elnaz Ataei, Atoosa Gharib et al.
Urology Case Reports
Testicular diseases and treatments
article

From pure testicular Teratoma to primitive neuroectodermal tumor: Successful management of Teratoma malignant transformation with widespread metastases in a young adult

Amir Alinejad Khorram, Navid Masoumi, Elnaz Ataei, Atoosa Gharib, Ali Amani‐Beni
article en

Abstract

Midline retroperitoneal masses in young males often present a diagnostic challenge, with metastases from testicular origins being a primary consideration. Beyond the initial pathology of testicular cancer, these masses can undergo transformation, including the development of teratomas. This report describes an unusual case of a calcified retroperitoneal mass originating from a testicular pure teratoma that underwent a rare transformation into a Primitive Neuroectodermal Tumor (PNET), comprising approximately 85 % of the tumor volume. The patient's successful treatment involved a comprehensive approach combining surgical resection and chemotherapy.

Urology Case ReportsVol. 56
Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 74%
Testicular diseases and treatments
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From pure testicular Teratoma to primitive neuroectodermal tumor: Successful management of Teratoma malignant transformation with widespread metastases in a young adult — Amir Alinejad Khorram, Navid Masoumi, et al. · Urology Case Reports (2024) | TGRS Research Map | TGRS