Metabolomic profiling integrated with molecular exploring delineates the action of Ligusticum chuanxiong hort. on migraine
To sum up, the present study firstly reveals that LCH plays a therapeutic role for migraine through glucose-glutamate-Nrf-2 axis, which might represent a promising approach in the development of advanced therapeutic strategies for migraine, and the LCH may be an effective drug or dietary supplement for relieving headache.
Authors
- Cheng Peng
- Fu Peng
- Ziwei Xing (ORCID: https://orcid.org/0000-0003-2506-0459)
- Yu Chen (ORCID: https://orcid.org/0000-0001-8636-4291)
- Feng Wan (ORCID: https://orcid.org/0000-0003-0047-724X)
- Dan Li
Institutions
- Sichuan University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.phymed.2024.155977
- Citations
- 11
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- National Natural Science Foundation of China
- Sichuan Province Science and Technology Support Program