Graphene Oxide-Based Antifungal Pesticide Delivery System for Tobacco Fungal Disease (Tobacco Target Spot) Control
In recent years, nanocarrier-based pesticide delivery systems have provided new possibilities for the efficient utilization of pesticides. In this research, we developed a hydroxypropyl-β-cyclodextrin-modified graphene oxide (GO-HP-β-CD) nanocarrier for pyraclostrobin (Pyr) delivery and studied its application for tobacco target spot disease control. GO-HP-β-CD has excellent pesticide-loading performance for Pyr (adsorption capacity of 1562.5 mg/g) and good water dispersibility and stability. Besides, GO-HP-β-CD shows pH-responsive release performance. In addition, GO-HP-β-CD also has better leaf affinity than Pyr, and it can effectively adhere to the leaf surface after simulated washing. The results of antifungal experiments indicate that GO-HP-β-CD-Pyr has a good preventive effect on tobacco target spot disease, and its EC<sub>50</sub> value is 0.384 mg/L, which is lower than Pyr. Specifically, this nanopesticide formulation does not contain toxic organic solvent or additive, so it has good environmental friendliness. Therefore, we believe that the GO-HP-β-CD-Pyr nanopesticide has brilliant potential in the prevention and control of tobacco diseases.
Authors
- Youfa Jiang (ORCID: https://orcid.org/0000-0002-7607-3543)
- Jian Shen (ORCID: https://orcid.org/0000-0002-9009-6151)
- Saijie Song (ORCID: https://orcid.org/0000-0002-3776-1634)
- Wei Jia (ORCID: https://orcid.org/0000-0002-3739-8994)
- Yi Luo (ORCID: https://orcid.org/0009-0002-3414-9148)
- Xuefeng Jiang (ORCID: https://orcid.org/0000-0002-1526-9470)
- He Shen (ORCID: https://orcid.org/0000-0002-9152-7945)
- Xiaoju Wu
- Guiji Yin
Institutions
- Nanjing Normal University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Yangtze River Pharmaceutical Group (China) (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Langmuir
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1021/acs.langmuir.4c02054
- Citations
- 10
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.84
Funders
- Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
- China National Tobacco Corporation
- Department of Science and Technology of Liaoning Province