The gene YEF3 function encoding translation elongation factor eEF3 is partially conserved across fungi
Given that most existing knowledge on fungal translation has only been obtained from <i>S. cerevisiae</i>, our findings beyond this organism showed variability in the elongation process in Fungi. We also proved that <i>eEF3</i> is essential in pathogenic fungi, opening the possibility of using eEF3 as a target to fight candidiasis.
Authors
- Alejandra García (ORCID: https://orcid.org/0000-0002-3040-612X)
- Greco Hernández (ORCID: https://orcid.org/0000-0002-5318-4443)
- Michael Altmann (ORCID: https://orcid.org/0000-0002-7378-9001)
- Giovanna Maldonado (ORCID: https://orcid.org/0000-0001-9247-8746)
- Rainer Fischer (ORCID: https://orcid.org/0000-0002-6704-2569)
- Irene Castaño (ORCID: https://orcid.org/0000-0002-5968-2101)
- Saturnino Herrero
Institutions
- University of Bern (CH)
- Institute for Scientific and Technological Research (MX)
- Instituto Nacional de Cancerología (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.3389/fmicb.2024.1438900
- Citations
- 1
- Primary Topic
- RNA and protein synthesis mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Instituto Nacional de Cancerología
- Deutsche Forschungsgemeinschaft
- Directorate for Biological Sciences