Comparison of combined intravenous and intra-arterial thrombolysis with intravenous thrombolysis alone in stroke patients undergoing mechanical thrombectomy: a propensity-matched analysis
The combined use of IAT and IVT thrombolysis in AIS-LVO patients undergoing MT is safe. Although the MT+IVT+ IAT group demonstrated lower rates of recanalization and early neurological improvement, long-term functional outcomes were favorable in this group suggesting a potential delayed benefit of IAT.
Authors
- Stacey Q Wolfe (ORCID: https://orcid.org/0000-0001-7603-2728)
- Shakeel Chowdhry (ORCID: https://orcid.org/0000-0002-9752-3291)
- Roberto Crosa (ORCID: https://orcid.org/0000-0001-6924-2161)
- Hidetoshi Matsukawa (ORCID: https://orcid.org/0000-0001-8229-4935)
- Pedro Navía (ORCID: https://orcid.org/0000-0002-6516-6090)
- Reade De Leacy (ORCID: https://orcid.org/0000-0001-9447-5338)
- Joshua William Osbun (ORCID: https://orcid.org/0000-0003-4308-9669)
- Fazeel Siddiqui (ORCID: https://orcid.org/0000-0001-7496-5567)
- Bhageeradh Mulpur (ORCID: https://orcid.org/0000-0002-7450-9964)
- Ilko Maier (ORCID: https://orcid.org/0000-0001-6988-8878)
- Atakan Orscelik (ORCID: https://orcid.org/0000-0001-6481-3076)
- Brian M. Howard (ORCID: https://orcid.org/0000-0001-9134-0817)
- David Altschul (ORCID: https://orcid.org/0000-0002-5130-1378)
- Conor Cunningham (ORCID: https://orcid.org/0000-0002-2628-4828)
- Alejandro M Spiotta (ORCID: https://orcid.org/0000-0002-7142-5538)
- Ali M. Alaraj (ORCID: https://orcid.org/0000-0002-1491-4634)
- Ramesh Grandhi (ORCID: https://orcid.org/0000-0001-9000-6083)
- Mohamad Ezzeldin (ORCID: https://orcid.org/0000-0001-7740-8774)
- Justin Robert Mascitelli (ORCID: https://orcid.org/0000-0001-9409-5810)
- Michael R. Levitt (ORCID: https://orcid.org/0000-0003-3612-3347)
- Adam Polifka (ORCID: https://orcid.org/0000-0003-4807-5274)
- Waleed Brinjikji (ORCID: https://orcid.org/0000-0001-5271-5524)
- Peter Kan (ORCID: https://orcid.org/0000-0001-6649-4128)
- Edgar Andres Samaniego (ORCID: https://orcid.org/0000-0003-2764-2268)
- Sameh Samir Elawady (ORCID: https://orcid.org/0000-0002-6537-0251)
- Nitin Goyal (ORCID: https://orcid.org/0000-0002-4699-0922)
- Rahim Abo Kasem (ORCID: https://orcid.org/0000-0002-9635-7471)
- Ali Mostafa Alawieh (ORCID: https://orcid.org/0000-0003-2601-8850)
- Ansaar Rai
- Daniele Giuseppe Romano (ORCID: https://orcid.org/0000-0002-7357-7770)
- Mohammad‐Mahdi Sowlat (ORCID: https://orcid.org/0000-0001-6777-4332)
- Hugo Cuellar (ORCID: https://orcid.org/0000-0002-8348-4535)
- Ergün Dağlıoğlu (ORCID: https://orcid.org/0000-0002-7162-3999)
- Isabel Fragata (ORCID: https://orcid.org/0000-0002-7037-7458)
- Charles Matouk (ORCID: https://orcid.org/0000-0003-3234-9541)
- Marios‐Nikos Psychogios
- Noah Nawabi
- Mark Moss
- Julio Isidor (ORCID: https://orcid.org/0000-0002-3138-3484)
- Min Park (ORCID: https://orcid.org/0000-0001-5204-5620)
- Robert M. Starke (ORCID: https://orcid.org/0000-0002-7608-0460)
- Shinichi Yoshimura (ORCID: https://orcid.org/0000-0001-5633-9132)
- Joon‐Tae Kim (ORCID: https://orcid.org/0000-0002-4116-4832)
- Omar Tanweer (ORCID: https://orcid.org/0000-0002-6544-5591)
- Richard A. Williamson
- Pascal Jabbour (ORCID: https://orcid.org/0000-0002-1544-4910)
Institutions
- Chonnam National University (KR)
- Allegheny Health Network (US)
- Mayo Clinic (US)
- Montefiore Medical Center (US)
- NorthShore University HealthSystem (US)
- Hyogo Medical University (JP)
- University of Miami (US)
- Thomas Jefferson University (US)
- Emory University (US)
- Medical University of South Carolina (US)
- University of Tennessee Health Science Center (US)
- The University of Texas at San Antonio Health Science Center (US)
- Bilkent University (TR)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- University of Washington (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Hospital Universitario La Paz (ES)
- University of Iowa Hospitals and Clinics (US)
- University Hospital of Basel (CH)
- West Virginia University Hospitals (US)
- Yale University (US)
- University of Florida (US)
- University of Illinois Chicago (US)
- Unidade Local de Saúde de São José (PT)
- Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona (IT)
- Neurological Surgery (US)
- Ankara Bilkent City Hospital (TR)
- University of Houston (US)
- Wake Forest University (US)
- University of Virginia (US)
- The University of Texas Medical Branch at Galveston (US)
- Louisiana State University Health Sciences Center New Orleans (US)
- Louisiana State University Health Sciences Center Shreveport (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of NeuroInterventional Surgery
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1136/jnis-2024-021975
- Citations
- 3
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Stryker
- Brain Aneurysm Foundation
- Penumbra