Use of extracellular vesicle microRNA profiles in patients with acute myeloid leukemia for the identification of novel biomarkers
Overall, our findings revealed that EV-derived miRNAs can serve as biomarkers for risk stratification and prognosis in AML. In addition, these EV-derived miRNA-based bioinformatic analyses could help efficiently identify mRNAs with biomarker potential, similar to the previous cell-based approach.
Authors
- Sunghoi Hong (ORCID: https://orcid.org/0000-0003-4926-1044)
- Ka‐Won Kang (ORCID: https://orcid.org/0000-0003-1462-0502)
- Yong Park (ORCID: https://orcid.org/0000-0001-7909-6639)
- Hyun Koo Kim (ORCID: https://orcid.org/0000-0001-7604-4729)
- Jeong‐An Gim (ORCID: https://orcid.org/0000-0001-7292-2520)
- Yeonho Choi (ORCID: https://orcid.org/0000-0003-2018-3599)
- Ji‐Ho Park (ORCID: https://orcid.org/0000-0002-0721-0428)
Institutions
- Korea Advanced Institute of Science and Technology (KR)
- Korea University (KR)
- Soonchunhyang University (KR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1371/journal.pone.0306962
- Citations
- 8
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- National Research Foundation
- Korea University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea