Lactate dehydrogenase-1 may play a key role in the brain energy disturbance caused by cryptococcal meningitis
Reduced levels of LDH1 in the brain of patients with CM may lead to increased lactate levels, decreased pyruvate and ATP levels, and negatively affect neuronal activity.
Authors
- Sijun Li (ORCID: https://orcid.org/0000-0002-6199-4307)
- Long Qian (ORCID: https://orcid.org/0000-0003-3728-7917)
- Jieling Chen (ORCID: https://orcid.org/0000-0001-7728-3959)
- Cailing Wei
- Zhizhong Huang (ORCID: https://orcid.org/0000-0002-3581-7331)
- Yanqing Zheng (ORCID: https://orcid.org/0000-0002-7809-5527)
- Jianglong Qin
- Qingdong Zhu (ORCID: https://orcid.org/0009-0003-3368-5296)
- Lanwei Nong (ORCID: https://orcid.org/0009-0004-7944-7186)
Institutions
- The Fourth People's Hospital (CN)
- The Second Nanning People's Hospital (CN)
- First People's Hospital of Nanning (CN)
- 303 Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.jmii.2024.08.009
- Citations
- 2
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Natural Science Foundation of China