Disability trajectories by progression independent of relapse activity status differ in pediatric, adult and late-onset multiple sclerosis
Age is relevant in determining disability progression in MS. POMS shows a less steep increase in EDSS scores over time than older patients. The effect of PIRA in accelerating EDSS progression is less pronounced in POMS than in AOMS and LOMS.
Authors
- Pietro Osvaldo Luigi Annovazzi (ORCID: https://orcid.org/0000-0003-0279-0707)
- Massimo Filippi (ORCID: https://orcid.org/0000-0002-5485-0479)
- Lucia Margari (ORCID: https://orcid.org/0000-0002-9203-3373)
- Diana Ferraro (ORCID: https://orcid.org/0000-0003-4818-3806)
- Roberto Bergamaschi (ORCID: https://orcid.org/0000-0002-1397-511X)
- Franco Granella
- Maria Gabriella Coniglio
- Tommaso Guerra (ORCID: https://orcid.org/0000-0002-5248-5981)
- Alessandra Lugaresi (ORCID: https://orcid.org/0000-0003-2902-5589)
- Emilio Portaccio (ORCID: https://orcid.org/0000-0002-9662-1762)
- Maria Pia Amato (ORCID: https://orcid.org/0000-0003-3325-3760)
- Pietro Iaffaldano (ORCID: https://orcid.org/0000-0003-2308-1731)
- Giovanna De Luca (ORCID: https://orcid.org/0000-0002-7693-2256)
- Damiano Paolicelli (ORCID: https://orcid.org/0000-0002-8645-1763)
- Marta Simone (ORCID: https://orcid.org/0000-0003-4381-4613)
- Francesco Patti (ORCID: https://orcid.org/0000-0002-6923-0846)
- Silvia Romano (ORCID: https://orcid.org/0000-0003-0499-8843)
- Carlo Pozzilli (ORCID: https://orcid.org/0000-0002-6360-4798)
- Maria Assunta Rocca (ORCID: https://orcid.org/0000-0003-2358-4320)
- Giacomo Lus (ORCID: https://orcid.org/0000-0002-9457-1124)
- Vincenzo Brescia Morra (ORCID: https://orcid.org/0000-0003-0462-9618)
- Claudio Gasperini
- Marika Vianello (ORCID: https://orcid.org/0009-0006-0864-7230)
- Paola Perini (ORCID: https://orcid.org/0009-0008-9628-1180)
- Giuseppe Lucisano
Institutions
- University of Parma (IT)
- University of Padua (IT)
- Vita-Salute San Raffaele University (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- University of Catania (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- CTO Andrea Alesini (IT)
- Don Carlo Gnocchi Foundation (IT)
- Federico II University Hospital (IT)
- Ospedale Madonna Delle Grazie (IT)
- Istituto delle Scienze Neurologiche di Bologna (IT)
- Tecnologie Avanzate (Italy) (IT)
- Ca' Foncello Hospital (IT)
- Carlo Forlanini Hospital (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Center for Outcomes Research and Clinical Epidemiology (IT)
- University of Florence (IT)
- University of Bari Aldo Moro (IT)
- Sapienza University of Rome (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1007/s00415-024-12638-0
- Citations
- 11
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.67