Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)
In summary, this work describes BRAF/MEK-inhibitor-resistant melanoma cells, allowing for better understanding the underlying mechanisms of resistance. The results may thus contribute to the development of new, more effective therapeutic strategies.
Authors
- Dorota Nowak (ORCID: https://orcid.org/0000-0002-6426-1686)
- Rafał Matkowski (ORCID: https://orcid.org/0000-0002-1705-5097)
- Magdalena Kot (ORCID: https://orcid.org/0000-0001-8374-2090)
- Aleksandra Simiczyjew (ORCID: https://orcid.org/0000-0002-6060-2375)
- Marcin Ziętek (ORCID: https://orcid.org/0000-0002-7890-3483)
- Justyna Wądzyńska (ORCID: https://orcid.org/0000-0002-0105-0021)
Institutions
- University of Wrocław (PL)
- Wroclaw Medical University (PL)
- Ludwik Hirszfeld Institute of Immunology and Experimental Therapy (PL)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1186/s12964-024-01788-3
- Citations
- 10
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- Narodowym Centrum Nauki