Unraveling the chemotherapeutic potential of taxifolin ruthenium-p-cymene complex in breast carcinoma: Insights into AhR signaling pathway in vitro and in vivo
In conclusion, the compound repressed the cancerous cellular viability, migration, and EMT via modulating the AhR/EGFR/ PI3K transduction pathway and the expression of EMT biomarkers such as N-cadherin, E-cadherin, thus eventually revoked the EMT facilitated metastasis of malignant cells.
Authors
- Abhijit Das (ORCID: https://orcid.org/0000-0002-5851-8457)
- Souvik Roy (ORCID: https://orcid.org/0000-0003-2980-0362)
- Barshana Bhattacharya
- Sakuntala Gayen (ORCID: https://orcid.org/0009-0007-6746-9857)
Institutions
- Saha Institute of Nuclear Physics (IN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1016/j.tranon.2024.102107
- Citations
- 3
- Primary Topic
- Mechanisms of cancer metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.70