Lymphocyte Infiltration Score and Spatial Characteristics Refined the Prognosis and Denosumab Treatment Responsiveness Indicators for Giant Cell Tumor of Bone
These findings suggest that LIS is a reliable predictive tool for clinically relevant outcomes and response to denosumab therapy in patients with GCTB. These parameters may prove to be useful in guiding prognostic risk stratification and therapeutic optimization for patients.
Authors
- Chao Xia (ORCID: https://orcid.org/0009-0001-7531-6005)
- Bo‐Wen Zheng (ORCID: https://orcid.org/0000-0002-9308-3794)
- Ming‐Xiang Zou (ORCID: https://orcid.org/0000-0002-4516-3917)
- Hua‐Qing Niu
- Guo‐Qiang Zhu
- Bo‐Yv Zheng
- Fusheng Liu (ORCID: https://orcid.org/0000-0003-1175-5209)
- Hailin Wu
Institutions
- Central South University (CN)
- Peking University (CN)
- Second Affiliated Hospital of Zhengzhou University (CN)
- Peking University People's Hospital (CN)
- First Affiliated Hospital of University of South China (CN)
- Central Hospital of Wuhan (CN)
- Second Xiangya Hospital of Central South University (CN)
- Xiangya Hospital Central South University (CN)
- University of South China (CN)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1200/po.24.00135
- Citations
- 6
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.82