Waste-derived Ca and Zn-based bimetallic (Ca/Zn) nanorods encapsulated chitosan-based haemostatic dressing bandage: A step towards waste to bandages

Controlling loss of blood during militant war, traumatic injury, and surgical procedures is the greatest challenge nowadays, which leads to death, thereby the necessity of hemostatic bandages. The present work focuses on the synthesis of waste-derived (WD)-Ca incorporated Zn nanorods encapsulated with chitosan polymers (CZC) to control the loss of blood as well as bacterial infection. The as-prepared CZC bandage was tested against various biochemical tests such as PBS absorption, hemolysis, adsorption of protein, platelets aggregation/adhesion, blood clotting ability, and antibacterial test assay. The data suggested that the CZC bandage has high biocompatibility, exceptional PBS absorption ability (∼1402%), platelets aggregation (∼65%) within 10 min of exposure, protein a loading ability (∼37 mg/cm 2 ), and ∼84% blood clotting within a 1 min of exposure. Moreover, the CZC bandage effectively kills/inhibits both E. Coli and S. aureus bacteria. Therefore, the prepared CZC bandage in this study is simple, economically viable, and sustainable development.

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Publication Details

Journal
Journal of Industrial and Engineering Chemistry
Published
2024-08-23
DOI
https://doi.org/10.1016/j.jiec.2024.08.035
Citations
5
Primary Topic
Hemostasis and retained surgical items
Type
article
Field-Weighted Citation Impact
2.27
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article

Waste-derived Ca and Zn-based bimetallic (Ca/Zn) nanorods encapsulated chitosan-based haemostatic dressing bandage: A step towards waste to bandages

Mohammad Ashfaq, Rishabh Anand Omar, Neetu Talreja, Pooja Thakur et al.
5 citations
Journal of Industrial and Engineering Chemistry
Hemostasis and retained surgical items
2.27
article

Waste-derived Ca and Zn-based bimetallic (Ca/Zn) nanorods encapsulated chitosan-based haemostatic dressing bandage: A step towards waste to bandages

Mohammad Ashfaq, Rishabh Anand Omar, Neetu Talreja, Pooja Thakur, Divya Chauhan
article en
5 citations

Abstract

Controlling loss of blood during militant war, traumatic injury, and surgical procedures is the greatest challenge nowadays, which leads to death, thereby the necessity of hemostatic bandages. The present work focuses on the synthesis of waste-derived (WD)-Ca incorporated Zn nanorods encapsulated with chitosan polymers (CZC) to control the loss of blood as well as bacterial infection. The as-prepared CZC bandage was tested against various biochemical tests such as PBS absorption, hemolysis, adsorption of protein, platelets aggregation/adhesion, blood clotting ability, and antibacterial test assay. The data suggested that the CZC bandage has high biocompatibility, exceptional PBS absorption ability (∼1402%), platelets aggregation (∼65%) within 10 min of exposure, protein a loading ability (∼37 mg/cm 2 ), and ∼84% blood clotting within a 1 min of exposure. Moreover, the CZC bandage effectively kills/inhibits both E. Coli and S. aureus bacteria. Therefore, the prepared CZC bandage in this study is simple, economically viable, and sustainable development.

Journal of Industrial and Engineering ChemistryVol. 143
Chandigarh University (IN), Alliance University (IN), Indian Institute of Technology Kanpur (IN)
Openalex Percentile: Top 11%
Hemostasis and retained surgical items
2.27
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