Tet1-mediated 5hmC regulates hippocampal neuroinflammation via wnt signaling as a novel mechanism in obstructive sleep apnoea leads to cognitive deficit
Activation of Wnt signaling pathway by hippocampal Tet1 is associated with cognitive dysfunction induced by IH.
Authors
- Yaru Kong
- Pengfei Ye
- Weiheng Yan (ORCID: https://orcid.org/0000-0001-6732-2985)
- Fan Liu (ORCID: https://orcid.org/0000-0002-9481-0797)
- Shan Wang (ORCID: https://orcid.org/0000-0002-6238-2644)
- Jie Ji (ORCID: https://orcid.org/0000-0003-4038-9180)
- Jun Tai (ORCID: https://orcid.org/0000-0001-8963-6790)
- Xiaojun Zhan
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Capital Institute of Pediatrics (CN)
- Beijing Children’s Hospital (CN)
- Children's Hospital of Capital Institute of Pediatrics (CN)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1186/s12974-024-03189-2
- Citations
- 9
- Primary Topic
- Neuroscience of respiration and sleep
- Type
- article
- Field-Weighted Citation Impact
- 2.47
Funders
- National Natural Science Foundation of China