Acyl-CoA thioesterase 13 (ACOT13) attenuates the progression of autosomal dominant polycystic kidney disease in vitro via triggering mitochondrial-related cell apoptosis
Collectively, our results showed that overexpression of <i>ACOT13</i> could suppress WT9-12 cell proliferation and trigger mitochondrial-mediated cell apoptosis, suggesting that <i>ACOT13</i> may exert a protective role in ADPKD.
Authors
- Na Du (ORCID: https://orcid.org/0009-0006-0805-1680)
- Luyao Sun (ORCID: https://orcid.org/0000-0001-7767-8408)
- Bin Wang (ORCID: https://orcid.org/0000-0001-9097-4578)
- Lihe Che
- Qi Yang (ORCID: https://orcid.org/0000-0002-4930-9661)
Institutions
- Beihua University (CN)
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Aging
- Published
- 2024-08-21
- DOI
- https://doi.org/10.18632/aging.206054
- Citations
- 1
- Primary Topic
- Genetic and Kidney Cyst Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.55