Molecular hydrogen supplementation in mice ameliorates lipopolysaccharide‐induced loss of interest
Hydrogen administration demonstrated a preventive effect against the LPS-induced loss of interest, suggesting a potential role in symptom prevention. However, it did not exhibit a suppressive effect on depressive symptoms in this particular model. These findings highlight the nuanced impact of hydrogen in the context of inflammation-induced psychiatric symptoms, indicating potential avenues for further exploration and research.
Authors
- Masanori Nagamine (ORCID: https://orcid.org/0000-0001-8882-4933)
- Aihide Yoshino (ORCID: https://orcid.org/0000-0001-5608-423X)
- Fumiho Asai
- Shinichi Tokuno (ORCID: https://orcid.org/0000-0002-2691-6979)
- Hiroyuki Toda (ORCID: https://orcid.org/0000-0003-4883-527X)
- Minori Koga (ORCID: https://orcid.org/0000-0003-3476-6883)
- Yuri Maezawa
- Ryuichi NAKAGAWA
- Mayumi Sato (ORCID: https://orcid.org/0000-0002-1664-6506)
Institutions
- National Defense Medical College (JP)
- Kanagawa University of Human Services (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences Reports
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1002/pcn5.70000
- Primary Topic
- Hydrogen's biological and therapeutic effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00