Calcinosis Cutis

Calcinosis cutis, characterized by the deposition of calcium in the skin or subcutaneous tissue, presents in 5 subtypes: dystrophic calcification, idiopathic calcification, iatrogenic calcification, metastatic calcification, and calciphylaxis. Among these, dystrophic calcinosis cutis is the most prevalent, typically resulting from local tissue damage or collagen alterations. This subtype is frequently associated with connective tissue diseases, notably scleroderma. Currently, no single effective therapy for calcinosis cutis exists, and the available treatments have limited supporting evidence. The following medical image shows classic physical examination findings of this rare condition.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2024-08-01
DOI
https://doi.org/10.7326/aimcc.2024.0272
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
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article

Calcinosis Cutis

James F. Howick, Mohammed Nadir Bhuiyan
Annals of Internal Medicine Clinical Cases
Inflammatory Myopathies and Dermatomyositis
article

Calcinosis Cutis

James F. Howick, Mohammed Nadir Bhuiyan
article en

Abstract

Calcinosis cutis, characterized by the deposition of calcium in the skin or subcutaneous tissue, presents in 5 subtypes: dystrophic calcification, idiopathic calcification, iatrogenic calcification, metastatic calcification, and calciphylaxis. Among these, dystrophic calcinosis cutis is the most prevalent, typically resulting from local tissue damage or collagen alterations. This subtype is frequently associated with connective tissue diseases, notably scleroderma. Currently, no single effective therapy for calcinosis cutis exists, and the available treatments have limited supporting evidence. The following medical image shows classic physical examination findings of this rare condition.

Annals of Internal Medicine Clinical CasesVol. 3(8)
Mayo Clinic (US)
Openalex Percentile: Top 79%
Inflammatory Myopathies and Dermatomyositis
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