Notch1 signaling pathway promotes growth and metastasis of gastric cancer via modulating CDH5
These results indicated Notch1 upregulation enhanced GC malignant behaviors by triggering CDH5, suggesting that targeting Notch1/CDH5 axis could be a potential therapeutic strategy for GC progression.
Authors
- Yongning Zhou (ORCID: https://orcid.org/0000-0002-7304-929X)
- Lingshan Zhou (ORCID: https://orcid.org/0000-0002-0095-3376)
- Yuwei Ye (ORCID: https://orcid.org/0009-0009-9533-8066)
- Min Liu (ORCID: https://orcid.org/0000-0002-1918-9072)
- Ya Zheng (ORCID: https://orcid.org/0000-0003-4476-1808)
- Qian Qiao (ORCID: https://orcid.org/0009-0009-2471-4423)
- Hongfang Liu (ORCID: https://orcid.org/0000-0002-5353-1580)
- Yuan Yang (ORCID: https://orcid.org/0000-0003-2212-4023)
- Yingying Mi
- Yuping Wang (ORCID: https://orcid.org/0009-0005-3160-3618)
Institutions
- Shanxi Medical University (CN)
- Shanxi Provincial People’s Hospital (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
- University of South China (CN)
Publication Details
- Journal
- Aging
- Published
- 2024-08-21
- DOI
- https://doi.org/10.18632/aging.206061
- Citations
- 4
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Lanzhou University
- National Natural Science Foundation of China
- Natural Science Foundation of Gansu Province