Exploring the protective effect and mechanism of icariside II on the bladder in a rat model of radiation cystitis based on transcriptome sequencing
ICAII may alleviate the bladder inflammatory response and inhibit the fibrosis process of bladder tissues through the regulation of H3F3C, ISG15, SPP1, and LCN2 targets and has a protective effect on the bladder of radioinjured rats. In particular, H3F3C may be one of the most promising therapeutic targets.
Authors
- Jilei Sun (ORCID: https://orcid.org/0009-0009-7588-4297)
- Xiang‐Xiang Zhang
- Zhitao Wei (ORCID: https://orcid.org/0000-0002-1285-9328)
- Yinhui Mao
- Yong Yang (ORCID: https://orcid.org/0000-0002-2907-3030)
- Zhuo Wang (ORCID: https://orcid.org/0000-0002-0641-6897)
- Juntao Sun (ORCID: https://orcid.org/0009-0008-6987-9902)
- Yongde Xu (ORCID: https://orcid.org/0000-0002-4298-7662)
- Chen-li Pan
Institutions
- Capital Medical University (CN)
- Changchun University of Chinese Medicine (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- International Journal of Radiation Biology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1080/09553002.2024.2386982
- Citations
- 1
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57