Novel injectable polypeptide nanoparticle encapsulated siRNA targeting TGF‐β1 and COX‐2 for localized fat reduction I: Preclinical in vitro and animal models
The results of these studies support the use of targeted siRNA therapy specifically targeting TGF-β1 and COX-2, for localized fat reduction, offering a potential minimally invasive alternative to current fat reduction methods.
Authors
- Patrick Lu (ORCID: https://orcid.org/0000-0002-4573-701X)
- Michael Molyneaux
- Mark S. Nestor (ORCID: https://orcid.org/0000-0002-8978-7932)
- Vishnu Bhupalam (ORCID: https://orcid.org/0009-0009-5045-0310)
- Nardin Awad
- J. Hetzel
Institutions
- University of Miami (US)
- Center for Clinical and Cosmetic Research (US)
- Sirnaomics (United States) (US)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1111/jocd.16535
- Citations
- 7
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 3.07