Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

The Editorial Office has been made aware of potential issues surrounding the scientific validity of the paper “Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression” DOI: 10.1042/CS20070250, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It has been noted that there appears to be similarities between some of the Western blot protein bands in Figure 2. Additionally, part of Figure 5 db+/db+ + rAVV Ang-1 panel appears similar to part of Figure 5B db+/db+ plus simvastatin panel from Bitto et al, 2008 (DOI: 10.1016/j.phrs.2008.01.005). The Editorial Office have contacted the authors, who have responded to the Journal's queries. The authors state that due to the age of the paper, the original data for Figure 2 is no longer available. As the concerns for Figure 2 and Figure 5B still stand, the Journal is issuing an expression of concern.

Publication Details

Journal
Clinical Science
Published
2024-08-01
DOI
https://doi.org/10.1042/cs-2007-0250_eoc
Citations
1
Primary Topic
Angiogenesis and VEGF in Cancer
Type
article
Field-Weighted Citation Impact
0.23
Controls
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article

Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

1 citations
Clinical Science
Angiogenesis and VEGF in Cancer
0.23
article

Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression

article en
1 citations

Abstract

The Editorial Office has been made aware of potential issues surrounding the scientific validity of the paper “Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression” DOI: 10.1042/CS20070250, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It has been noted that there appears to be similarities between some of the Western blot protein bands in Figure 2. Additionally, part of Figure 5 db+/db+ + rAVV Ang-1 panel appears similar to part of Figure 5B db+/db+ plus simvastatin panel from Bitto et al, 2008 (DOI: 10.1016/j.phrs.2008.01.005). The Editorial Office have contacted the authors, who have responded to the Journal's queries. The authors state that due to the age of the paper, the original data for Figure 2 is no longer available. As the concerns for Figure 2 and Figure 5B still stand, the Journal is issuing an expression of concern.

Clinical ScienceVol. 138(16)
Zero hunger
Openalex Percentile: Top 43%
Angiogenesis and VEGF in Cancer
0.23
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Expression of Concern: Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression · Clinical Science (2024) | TGRS Research Map | TGRS