Low-dose apatinib optimizes the vascular normalization and enhances the antitumor effect of PD-1 inhibitor in gastric cancer
Low-dose apatinib enhances the antitumor effect of PD-1 inhibitor by normalizing tumor-related blood vessels, alleviating intratumor hypoxia and altering immunosuppressive microenvironment (IM).
Authors
- Kelong Tao (ORCID: https://orcid.org/0000-0001-8080-1200)
- Chen‐Yu Chen (ORCID: https://orcid.org/0000-0003-4519-8391)
- Meng He (ORCID: https://orcid.org/0009-0009-3922-6457)
- Tao Feng (ORCID: https://orcid.org/0009-0006-9560-5441)
- Guangen Xu (ORCID: https://orcid.org/0009-0000-7875-5698)
Institutions
- Shaoxing University (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2024-08-01
- DOI
- https://doi.org/10.21037/tcr-23-2328
- Citations
- 3
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- Shaoxing Bureau of Science and Technology
- Department of Health of Zhejiang Province