Metformin enhances the survival ability of ovarian granulosa cells in polycystic ovary syndrome by promoting <scp>LINC00548</scp> to suppress <scp>androgen receptor</scp>/klotho pathway
Overall, this study discovers that Met enhances the survival ability of OGCs in PCOS by elevating LINC00548 expression to suppress AR/klotho pathway.
Authors
- Guoping Xiong (ORCID: https://orcid.org/0000-0002-3216-0506)
- Gang Lei (ORCID: https://orcid.org/0000-0001-8656-965X)
- Yanru Yao (ORCID: https://orcid.org/0009-0008-6771-555X)
- Guangxin Pan (ORCID: https://orcid.org/0000-0002-8210-0026)
- Pei Zhang (ORCID: https://orcid.org/0000-0003-0608-5677)
- Li Zhang (ORCID: https://orcid.org/0000-0002-2574-4474)
- Sha Li (ORCID: https://orcid.org/0000-0002-4301-7158)
Institutions
- Central Hospital of Wuhan (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of obstetrics and gynaecology research
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1111/jog.16060
- Citations
- 1
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.54