Dynamic quantitative monitoring of cerebrospinal fluid monoamine neurotransmitter markers during the modeling process of chronic stress‐induced depression in monkeys ( <i>Macaca mulatta</i> )

This study is the first to observe the long-term dynamic relationship between early adversity, chronic stress, adolescent depression, and CSF monoamine concentrations. The research suggests that MS and chronic stress play an undeniable role in the pathogenesis of depression and that concentrations of HVA and dihydroxyphenylacetic acid are likely to serve as early markers of depressive-like symptoms in macaques.

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Publication Details

Journal
Brain and Behavior
Published
2024-08-01
DOI
https://doi.org/10.1002/brb3.3636
Citations
2
Primary Topic
Stress Responses and Cortisol
Type
article
Field-Weighted Citation Impact
0.58

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article

Dynamic quantitative monitoring of cerebrospinal fluid monoamine neurotransmitter markers during the modeling process of chronic stress‐induced depression in monkeys ( Macaca mulatta )

Si‐Yu Li, Xiaoli Feng
2 citations
Brain and Behavior
Stress Responses and Cortisol
0.58
article

Dynamic quantitative monitoring of cerebrospinal fluid monoamine neurotransmitter markers during the modeling process of chronic stress‐induced depression in monkeys ( Macaca mulatta )

Si‐Yu Li, Xiaoli Feng
article en
2 citations

Abstract

This study is the first to observe the long-term dynamic relationship between early adversity, chronic stress, adolescent depression, and CSF monoamine concentrations. The research suggests that MS and chronic stress play an undeniable role in the pathogenesis of depression and that concentrations of HVA and dihydroxyphenylacetic acid are likely to serve as early markers of depressive-like symptoms in macaques.

Brain and BehaviorVol. 14(8)
Kunming Institute of Zoology (CN), Chinese Academy of Sciences (CN), Kunming Medical University (CN)
Chinese Academy of Sciences, Kunming Medical University, Natural Science Foundation of Yunnan Province, Yunnan Provincial Science and Technology Department, Institute of Zoology, Chinese Academy of Sciences, Kunming Institute of Zoology, Chinese Academy of Sciences
Good health and well-being
Openalex Percentile: Top 35%
Stress Responses and Cortisol
0.58
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