Baseline tumour vessel perfusion as a non-invasive predictive biomarker for immune checkpoint therapy in non-small-cell lung cancer
OMP, derived from routine CT examination, could serve as a non-invasive and cost-effective biomarker to predict NSCLC patient response to immune checkpoint inhibitor-based therapy. OMP could be used alone or in combination with other biomarkers to improve precision immunotherapy.
Authors
- Liang Sun (ORCID: https://orcid.org/0000-0002-5213-6941)
- Hongtai Shi (ORCID: https://orcid.org/0000-0002-3815-8239)
- Jiya Sun (ORCID: https://orcid.org/0000-0003-2191-6686)
- Rakesh K. Jain (ORCID: https://orcid.org/0000-0001-7571-3548)
- Junhui Wang (ORCID: https://orcid.org/0000-0002-5493-391X)
- Bo Zhu (ORCID: https://orcid.org/0000-0001-5221-6901)
- Qingzhu Jia (ORCID: https://orcid.org/0000-0002-6862-5395)
- Yuhui Huang (ORCID: https://orcid.org/0000-0003-1985-3575)
- Yunpeng Yang (ORCID: https://orcid.org/0000-0001-6987-2219)
- Ying Wang (ORCID: https://orcid.org/0000-0003-2121-7025)
- Zhenhua Liu (ORCID: https://orcid.org/0000-0002-0066-5163)
- Li Zhang (ORCID: https://orcid.org/0000-0002-8101-672X)
- Peng Fan
- Songbing Qin (ORCID: https://orcid.org/0000-0001-7056-1741)
- Ke Ma (ORCID: https://orcid.org/0000-0001-9184-3422)
- Wei Xu (ORCID: https://orcid.org/0009-0009-0310-7843)
- Liansai Sun
Institutions
- Harvard University (US)
- Army Medical University (CN)
- Sun Yat-sen University (CN)
- Nantong University (CN)
- Soochow University (CN)
- Massachusetts General Hospital (US)
- Yancheng First People's Hospital (CN)
- Yancheng Third People's Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- First Affiliated Hospital of Soochow University (CN)
- Innovative Biologics (United States) (US)
Publication Details
- Journal
- BMJ Oncology
- Published
- 2024-08-01
- DOI
- https://doi.org/10.1136/bmjonc-2024-000473
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- National Foundation for Cancer Research
- Advanced Medical Research Foundation
- National Natural Science Foundation of China
- Soochow University
- Priority Academic Program Development of Jiangsu Higher Education Institutions