Inherited genetic predisposition and imaging concordance in degenerative lumbar scoliosis patients and their descendants
Genetic influences are significant in the onset of DLS, with affected families showing similar scoliosis patterns and identical apex vertebrae. Moreover, individuals with genetic mutations tend to have more pronounced vertebral rotation and at a higher risk of developing scoliosis.
Authors
- Weishi Li (ORCID: https://orcid.org/0000-0001-9512-5436)
- Yilei Liu
- Yachong Huo (ORCID: https://orcid.org/0000-0002-7226-1707)
- Wenyuan Ding (ORCID: https://orcid.org/0000-0002-7257-4316)
- Zhenguo Shang (ORCID: https://orcid.org/0000-0002-9911-0968)
- Hui Wang (ORCID: https://orcid.org/0000-0001-9198-9309)
- Di Zhang (ORCID: https://orcid.org/0009-0009-9455-3207)
- Hongru Yuan
Institutions
- Hebei Medical University (CN)
- Peking University (CN)
- Third Hospital of Hebei Medical University (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1186/s13018-024-05000-7
- Citations
- 3
- Primary Topic
- Scoliosis diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Natural Science Foundation of Hebei Province