The role of tRF-Val-CAC-010 in lung adenocarcinoma: implications for tumorigenesis and metastasis
This study demonstrates that tRF-Val-CAC-010 promotes proliferation, migration, and invasion of LUAD cells and induces apoptosis in vitro, however, its specific effects on the cell cycle require further elucidation. Additionally, tRF-Val-CAC-010 enhances tumor formation and metastasis in vivo. Therefore, tRF-Val-CAC-010 may serve as a novel diagnostic biomarker and potential therapeutic target for LUAD.
Authors
- Yue Cao (ORCID: https://orcid.org/0000-0002-9640-0003)
- Wanpu Wang (ORCID: https://orcid.org/0000-0002-7109-7714)
- Zheng-Bo Long
- Li Wang (ORCID: https://orcid.org/0000-0002-9806-6176)
- Juanjuan Zhang (ORCID: https://orcid.org/0000-0003-0864-6343)
- Hui Yang (ORCID: https://orcid.org/0000-0003-2446-278X)
- Yuxin Xie (ORCID: https://orcid.org/0000-0002-7384-2386)
- Lilin Luo (ORCID: https://orcid.org/0000-0001-7417-2401)
- Linhui Li (ORCID: https://orcid.org/0000-0002-0311-3786)
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-08-21
- DOI
- https://doi.org/10.1186/s12885-024-12800-x
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.23