Transcriptome analysis of the aged SAMP8 mouse model of Alzheimer’s disease reveals novel molecular targets of formononetin protection
Neuroinflammation and decreased antioxidant and SIRT-1 signaling contributed to cognitive deficits in aged SAMP8 mice, which are potential therapeutic targets of formononetin in combination with other therapies.
Authors
- Jie Liu (ORCID: https://orcid.org/0000-0002-4530-1443)
- Bo Liu (ORCID: https://orcid.org/0000-0001-5627-6581)
- Di Cui
- Jing-Shan Shi
Institutions
- Zunyi Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fphar.2024.1440515
- Citations
- 6
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.96
Funders
- Guizhou Science and Technology Department