Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
Netrins are widely perceived as procancer proteins; however, we uncover an anticancer function for Netrin-1 and its receptor UNC5B.
Authors
- Katherine Huang (ORCID: https://orcid.org/0000-0003-0248-6078)
- Patrick Mehlen (ORCID: https://orcid.org/0000-0003-1743-5417)
- Rod Bremner (ORCID: https://orcid.org/0000-0001-9184-7212)
- Benjamin Ducarouge (ORCID: https://orcid.org/0000-0002-6701-0508)
- Louis G. Dela Pena
- Joel D. Pearson (ORCID: https://orcid.org/0009-0002-7559-4897)
Institutions
- Mount Sinai Hospital (CA)
- University of Toronto (CA)
- Lunenfeld-Tanenbaum Research Institute (CA)
- CancerCare Manitoba (CA)
- Netris Pharma (France) (FR)
- Centre Léon Bérard (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Sinai Health System (CA)
- University of Manitoba (CA)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1158/2767-9764.crc-24-0101
- Citations
- 2
- Primary Topic
- Hippo pathway signaling and YAP/TAZ
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- Cancer Research Society
- CancerCare Manitoba Foundation
- Krembil Foundation
- Centre Léon Bérard
- Canadian Institutes of Health Research