Serum biomarker-based risk model construction for primary Sjögren’s syndrome with interstitial lung disease
There were significant differences in serum marker levels between pSS-ILD and pSS-N-ILD cases. The combination of anti-CCP, IL-17, IL-12p70, and IL-5 might be a potential risk predictor for pSS-ILD occurrence. The cytokines might be involved in the development and progression of pSS-ILD. These results would provide new therapeutic targets for pSS-ILD treatment.
Authors
- Juan Shi (ORCID: https://orcid.org/0000-0001-9151-9980)
- Xiuzhi Zhang (ORCID: https://orcid.org/0000-0003-2854-9938)
- Xiaoli Liu (ORCID: https://orcid.org/0000-0003-0986-6487)
- Huiling Wang
- Shiqing Li (ORCID: https://orcid.org/0000-0001-9883-4553)
- Xia Zhang (ORCID: https://orcid.org/0000-0002-4811-3229)
Institutions
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Nanyang Medical College (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fmolb.2024.1448946
- Citations
- 3
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- Natural Science Foundation of Henan Province