Development and validation of a novel high-performance liquid chromatography (HPLC) method for the detection of related substances of pralsetinib, a new anti-lung cancer drug

The chromatographic method developed in this study can be utilized for the detection of pralsetinib and its impurities, offering a crucial reference for research on the quality of pralsetinib.

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Publication Details

Journal
Frontiers in Chemistry
Published
2024-08-21
DOI
https://doi.org/10.3389/fchem.2024.1450692
Citations
5
Primary Topic
Chronic Lymphocytic Leukemia Research
Type
article
Field-Weighted Citation Impact
2.19

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article

Development and validation of a novel high-performance liquid chromatography (HPLC) method for the detection of related substances of pralsetinib, a new anti-lung cancer drug

Yonghong Zhu, Wenyi Wu, Jisu Qin, Liangliang Cai
5 citations
Frontiers in Chemistry
Chronic Lymphocytic Leukemia Research
2.19
article

Development and validation of a novel high-performance liquid chromatography (HPLC) method for the detection of related substances of pralsetinib, a new anti-lung cancer drug

Yonghong Zhu, Wenyi Wu, Jisu Qin, Liangliang Cai
article en
5 citations

Abstract

The chromatographic method developed in this study can be utilized for the detection of pralsetinib and its impurities, offering a crucial reference for research on the quality of pralsetinib.

Frontiers in ChemistryVol. 12
Nantong University (CN), Affiliated Hospital of Nantong University (CN), China National Pharmaceutical Group Corporation (China) (CN)
Jiangsu Postdoctoral Research Foundation
Good health and well-being
Openalex Percentile: Top 12%
Chronic Lymphocytic Leukemia Research
2.19
DOIOpen Access PDFOpenAlex
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