Pathological response and safety of albumin-bound paclitaxel as a neoadjuvant treatment for HER2-positive breast cancer compared to docetaxel combined with anti-HER2 therapy: a real-world study

Our real-world study revealed that nab-paclitaxel combined with anti-HER2 therapy was an effective neoadjuvant therapy for HER2-positive breast cancer. The multivariate analysis revealed that chemotherapy drugs, clinical stage, ER status, and Ki-67 level was the significant factor influencing treatment outcome. These findings offer a valuable reference for the neoadjuvant treatment of patients with HER2-positive breast cancer.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-08-21
DOI
https://doi.org/10.3389/fonc.2024.1412051
Citations
3
Primary Topic
Cancer Treatment and Pharmacology
Type
article
Field-Weighted Citation Impact
0.85
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article

Pathological response and safety of albumin-bound paclitaxel as a neoadjuvant treatment for HER2-positive breast cancer compared to docetaxel combined with anti-HER2 therapy: a real-world study

Zhidong Lyu, Linlin Gao
3 citations
Frontiers in Oncology
Cancer Treatment and Pharmacology
0.85
article

Pathological response and safety of albumin-bound paclitaxel as a neoadjuvant treatment for HER2-positive breast cancer compared to docetaxel combined with anti-HER2 therapy: a real-world study

Zhidong Lyu, Linlin Gao
article en
3 citations

Abstract

Our real-world study revealed that nab-paclitaxel combined with anti-HER2 therapy was an effective neoadjuvant therapy for HER2-positive breast cancer. The multivariate analysis revealed that chemotherapy drugs, clinical stage, ER status, and Ki-67 level was the significant factor influencing treatment outcome. These findings offer a valuable reference for the neoadjuvant treatment of patients with HER2-positive breast cancer.

Frontiers in OncologyVol. 14
Qingdao University (CN), Affiliated Hospital of Qingdao University (CN)
Good health and well-being
Openalex Percentile: Top 23%
Cancer Treatment and Pharmacology
0.85
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