Altered activation patterns of the sensory-motor cortex in patients with knee osteoarthritis during knee isokinetic movement at different speeds
Contralateral activation of the sensorimotor cortex exists during unilateral knee movement, but in KOA patients, this contralateral cortical activation is suppressed. Furthermore, the clinical pain and dysfunction in KOA patients are associated with activation levels of specific brain regions. These findings can provide a better understanding of KOA brain science and are expected to contribute to the development of central intervention for the disease.
Authors
- Tao Ying (ORCID: https://orcid.org/0000-0001-5950-9993)
- Tiantian Liu (ORCID: https://orcid.org/0000-0002-8654-9912)
- Lixi Chu (ORCID: https://orcid.org/0000-0002-4348-3570)
- Kun Yang (ORCID: https://orcid.org/0000-0002-2011-7084)
- Haichen Xu (ORCID: https://orcid.org/0009-0006-0156-9583)
- Xiaoming Yu (ORCID: https://orcid.org/0000-0002-5227-2062)
- Liming Jiang (ORCID: https://orcid.org/0000-0001-7773-0149)
- Lei Yin (ORCID: https://orcid.org/0000-0002-4543-4510)
- Yuwu Ding
- Xubo Wu (ORCID: https://orcid.org/0000-0002-7593-6626)
- Bingli Liu
- Changfeng Cheng
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
- Seventh People's Hospital of Shanghai (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fbioe.2024.1444731
- Citations
- 6
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 2.82