Clinicopathologic features and surgical treatment prognosis of esophageal carcinosarcoma

Carcinosarcoma is a rare esophageal tumor, accounting for approximately 0.27-2.8% of malignant esophageal tumors. Histologically, the biphasic pattern is a crucial diagnostic feature, although the carcinomatous component may not always be evident, especially in limited biopsies, leading to potential misclassification as pure sarcoma or squamous cell carcinoma. Despite its large volume and cellular atypia, carcinosarcoma carries a favorable prognosis. Complete surgical resection of the tumor and regional lymph node dissection is the preferred treatment approach for esophageal carcinosarcoma.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-08-21
DOI
https://doi.org/10.3389/fonc.2024.1387611
Citations
2
Primary Topic
Metastasis and carcinoma case studies
Type
article
Field-Weighted Citation Impact
0.84

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article

Clinicopathologic features and surgical treatment prognosis of esophageal carcinosarcoma

Guang Han, Weiguang Jia, Quan Chen, Bingbing Wu et al.
2 citations
Frontiers in Oncology
Metastasis and carcinoma case studies
0.84
article

Clinicopathologic features and surgical treatment prognosis of esophageal carcinosarcoma

Guang Han, Weiguang Jia, Quan Chen, Bingbing Wu, Hailan Wang, Pei Yin, Yiming Zheng, Peng Zhang, Xia Chen, Pengcheng Wang, Pengfei Ge, Fuxing Liu, Fei Sun, Kaijin Lu, Jiangfeng Shen, Fei Wang
article en
2 citations

Abstract

Carcinosarcoma is a rare esophageal tumor, accounting for approximately 0.27-2.8% of malignant esophageal tumors. Histologically, the biphasic pattern is a crucial diagnostic feature, although the carcinomatous component may not always be evident, especially in limited biopsies, leading to potential misclassification as pure sarcoma or squamous cell carcinoma. Despite its large volume and cellular atypia, carcinosarcoma carries a favorable prognosis. Complete surgical resection of the tumor and regional lymph node dissection is the preferred treatment approach for esophageal carcinosarcoma.

Frontiers in OncologyVol. 14
Nantong University (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Nanjing Medical University (CN)
Nanjing Medical University
Good health and well-being
Openalex Percentile: Top 25%
Metastasis and carcinoma case studies
0.84
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Clinicopathologic features and surgical treatment prognosis of esophageal carcinosarcoma — Guang Han, Weiguang Jia, et al. · Frontiers in Oncology (2024) | TGRS Research Map | TGRS