Germline multigene panel testing in acute and chronic pancreatitis
The highest prevalence of pathogenic variants is seen in younger individuals with a positive family history of pancreatitis. However, clinically meaningful results are identified in older subjects, suggesting that genetic counseling and testing should be considered for all age groups.
Authors
- Somashekar G. Krishna (ORCID: https://orcid.org/0000-0001-5748-7890)
- Yevgeniya Gokun
- Phil A. Hart
- Sarah Poll (ORCID: https://orcid.org/0000-0001-7324-9825)
- J. Royce Groce
- Josie Baker
- Brandie Heald (ORCID: https://orcid.org/0000-0003-4227-3675)
- Georgios I. Papachristou (ORCID: https://orcid.org/0000-0001-9915-703X)
- Peter P. Stanich (ORCID: https://orcid.org/0000-0002-6844-640X)
- Rachel Pearlman (ORCID: https://orcid.org/0000-0002-9293-5860)
- Maegan E. Roberts (ORCID: https://orcid.org/0000-0002-0292-2557)
- Mitchell L. Ramsey (ORCID: https://orcid.org/0000-0002-6430-1924)
- Samuel Han (ORCID: https://orcid.org/0000-0001-7373-7984)
- Peter J. Lee (ORCID: https://orcid.org/0000-0002-0510-8980)
- Luis F. Lara (ORCID: https://orcid.org/0000-0001-5123-5932)
Institutions
- The Ohio State University Wexner Medical Center (US)
- Invitae (United States) (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1371/journal.pone.0307076
- Citations
- 5
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.86