Individual-level Data to Accompany “Recovery of Ventilatory and Metabolic Responses to Hypoxia in Neonatal Rats After Chronic Hypoxia”

Rat pups were exposed to 3 days of chronic hypoxia (12% O2) beginning shortly after birth. Ventilation (head-body plethysmography) and metabolic CO2 production (respirometry) were then measured in normoxia (21% O2, balance N2) and during an acute hypoxic challenge (15b minutes in 12% O2, balance N2) immediately following chronic hypoxia and after 1, 4-5, and 7 d in room air; different individuals were studied at each age. The linked data files contain the individual-level ventilation and CO2 production data. The full methods and summary data are available in the peer-reviewed article: Bavis RW, Lee DI, Kinnally AC, Puxton PE., 2024. Recovery of ventilatory and metabolic responses to hypoxia in neonatal rats after chronic hypoxia. Respiratory Physiology and Neurobiology, 329: 104317. https://doi.org/10.1016/j.resp.2024.104317 This article will be freely be available to download from PubMed Central on 11/1/2025 here: https://pubmed.ncbi.nlm.nih.gov/39187051/