CAR-T therapy pulmonary adverse event profile: a pharmacovigilance study based on FAERS database (2017–2023)
This study comprehensively analyzed the PAEs reported in the FAERS database among recipients of CAR-T cell therapy, revealing conditions such as hypoxia, respiratory failure, pleural effusion, and atelectasis. These CAR-T cell therapy-associated events are clinically significant and merit the attention of clinicians and researchers.
Authors
- Xinya Liu (ORCID: https://orcid.org/0000-0001-7813-3151)
- Mengjiao Gao
- Yuanming Zhang (ORCID: https://orcid.org/0000-0003-1370-4181)
- Yun Jiang (ORCID: https://orcid.org/0009-0004-1673-6204)
- Li Wu (ORCID: https://orcid.org/0009-0009-7680-616X)
- Jian Yu
- Jing Shi (ORCID: https://orcid.org/0009-0009-9498-5077)
Institutions
- Xinjiang Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Tumor Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fphar.2024.1434231
- Citations
- 5
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.41
Funders
- Natural Science Foundation of Xinjiang