Genetically predicted the causal relationship between gut microbiota and the risk of polymyositis/dermatomyositis: a Mendelian randomization analysis
We establish causal relationships between <i>Ruminococcaceae</i>, <i>Sutterella</i>, <i>Anaerotruncus</i> with DM, <i>Alloprevotella</i>, <i>Ruminococcaceae</i> UCG003, and <i>Dialister</i> with PM. Common microbiota, like <i>Ruminococcaceae</i>, have significant clinical implications. These findings open up greater possibilities for the gut microbiota to contribute to the development of PM/DM and for future monitoring of the gut microbiota in patients with PM/DM.
Authors
- Xinlei Geng (ORCID: https://orcid.org/0000-0002-3095-9277)
- Shilei Lin
- Keyi Fan (ORCID: https://orcid.org/0000-0002-1820-9107)
- Jialin Hou (ORCID: https://orcid.org/0000-0002-6983-5829)
- Heyi Zhang (ORCID: https://orcid.org/0000-0003-0443-3367)
- Sheng‐Xiao Zhang (ORCID: https://orcid.org/0000-0003-1341-7588)
- Xi-Yue Ma
- Xiaofeng Li (ORCID: https://orcid.org/0000-0002-8899-1886)
- Liu Liu
- Meilin Guo
- Yanna Niu
- Yaochen Zhang
Institutions
- Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fmicb.2024.1409497
- Citations
- 1
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shanxi Province