Colorectal cancer-specific microbiome in peripheral circulation and cancer tissues
This study has found significant alterations in the microbial compositions and diversities in CRC and CRC-specific microbial species in both circulation and cancer tissues, which may serve as promising biomarkers for the screening, diagnosis and prognosis prediction of CRC. In particular, CRC-specific bacterial taxa are promising markers, holding transformative potentials in establishing personalized screening and risk stratification, refining much earlier non-invasive diagnostic approaches, and enhancing diagnostic sensitivity.
Authors
- Shushan Yan (ORCID: https://orcid.org/0000-0002-8194-6409)
- Wenqing Dai
- Wenchang Sun (ORCID: https://orcid.org/0000-0001-7237-1511)
- Haobin Zhao
- Tie Liu (ORCID: https://orcid.org/0000-0001-6213-0933)
- Yuxin Zhu
- Honggang Wang (ORCID: https://orcid.org/0000-0002-4802-6133)
- Donghua Xu (ORCID: https://orcid.org/0000-0002-9146-7858)
- Sun Jun-xi
- Lu Zhao (ORCID: https://orcid.org/0000-0003-4972-8695)
- Chunbo Zhao (ORCID: https://orcid.org/0000-0003-0820-9960)
Institutions
- Tulane University (US)
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Weifang People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-08-21
- DOI
- https://doi.org/10.3389/fmicb.2024.1422536
- Citations
- 2
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.47