Hematological, inflammatory and serological responses among COVID-19 patients admitted to intensive care unit

<b>Aim:</b> To correlate hematological, inflammatory indicators and serological responses among COVID-19 patients to point out the significant biomarkers for disease management and prognosis.<b>Materials & methods:</b> Standard analytical and molecular methods were used to assess various inflammatory and serological Responses among COVID-19 patients (ICU- (n = 99) and non-ICU patients (n = 64) as compared with health control (n = 40).<b>Results:</b> Significant differences in the Hb, WBC, Lymphocyte count, CRP and serum ferritin (<i>p</i> < 0.05) were observed. Patients' IgM/IgG antibodies against SARS-CoV-2 were associated with increased CRP, LDH and serum ferritin levels.<b>Conclusion:</b> A significant association between serum IgG/IgM and ICU admission was observed. Although serum ferritin and LDH can offer information about the extent of inflammation, they are exclusive factors for ICU admission.