Long‐term safety and efficacy of glucagon‐like peptide‐1 receptor agonists in individuals with obesity and without type 2 diabetes: A global retrospective cohort study

In this large observational study, GLP-1 RAs showed long-term protective effects on cardiovascular health, renal outcomes and adverse events in individuals with obesity and without T2D. Our findings suggest that GLP-1 RAs may offer a comprehensive approach to managing obesity and its related comorbidities, potentially improving overall health and survival in this population.

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Publication Details

Journal
Diabetes Obesity and Metabolism
Published
2024-08-22
DOI
https://doi.org/10.1111/dom.15869
Citations
29
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
10.37

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article

Long‐term safety and efficacy of glucagon‐like peptide‐1 receptor agonists in individuals with obesity and without type 2 diabetes: A global retrospective cohort study

Chung‐Hsing Wang, Shun‐Fa Yang, Pen‐Hua Su, Wen‐Ling Liao et al.
29 citations
Diabetes Obesity and Metabolism
Diabetes Treatment and Management
10.37
article

Long‐term safety and efficacy of glucagon‐like peptide‐1 receptor agonists in individuals with obesity and without type 2 diabetes: A global retrospective cohort study

Chung‐Hsing Wang, Shun‐Fa Yang, Pen‐Hua Su, Wen‐Ling Liao, Chieh‐Chen Huang, Jing‐Yang Huang, Yu‐Nan Huang, Yu‐Jung Lin
article en
29 citations

Abstract

In this large observational study, GLP-1 RAs showed long-term protective effects on cardiovascular health, renal outcomes and adverse events in individuals with obesity and without T2D. Our findings suggest that GLP-1 RAs may offer a comprehensive approach to managing obesity and its related comorbidities, potentially improving overall health and survival in this population.

Diabetes Obesity and MetabolismVol. 26(11)
National Chung Hsing University (TW), China Medical University (TW), Tzu Chi University (TW), Tzu Chi Foundation (TW), Chung Shan Medical University Hospital (TW), China Medical University Hospital (TW), Chung Shan Medical University (TW)
Chung Shan Medical University Hospital
Good health and well-being
Openalex Percentile: Top 1%
Diabetes Treatment and Management
10.37
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Long‐term safety and efficacy of glucagon‐like peptide‐1 receptor agonists in individuals with obesity and without type 2 diabetes: A global retrospective cohort study — Chung‐Hsing Wang, Shun‐Fa Yang, et al. · Diabetes Obesity and Metabolism (2024) | TGRS Research Map | TGRS