Calpeptin improves the cognitive function in Alzheimer's disease‐like complications of diabetes mellitus rats by regulating <scp>TXNIP</scp>/<scp>NLRP3</scp> inflammasome
These data demonstrated that calpeptin treatment alleviated AD-like symptoms in DM rats through regulating TXNIP/NLRP3 inflammasome. Thus, calpeptin may be a potential drug to treat AD-like complications of diabetes mellitus.
Authors
- Luyao Qiao (ORCID: https://orcid.org/0000-0001-9463-5848)
- Gege Wang (ORCID: https://orcid.org/0000-0002-8032-4640)
- Tianpei Li (ORCID: https://orcid.org/0000-0001-5232-7708)
- Shouqin Yi
- Xin Pan (ORCID: https://orcid.org/0000-0003-1437-2780)
- Xu Liu
- Jun Min (ORCID: https://orcid.org/0000-0001-6380-3351)
- Min Li (ORCID: https://orcid.org/0009-0007-3630-4742)
- Zhenyu Tang (ORCID: https://orcid.org/0000-0003-4728-3397)
- Huahui Le
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1111/jdi.14292
- Citations
- 8
- Primary Topic
- Calpain Protease Function and Regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province
- Health Commission of Jiangxi Province