Identification of Schistosoma haematobium and Schistosoma mansoni linear B-cell epitopes with diagnostic potential using in silico immunoinformatic tools and peptide microarray technology
One peptide with a good diagnostic performance and nine peptides with acceptable diagnostic performances were identified using the immunoinformatic approach and peptide microarray validation. There is need for evaluation of the peptides with true negatives and a good standard positive reference.
Authors
- Marble Manuwa
- Arthur Vengesai (ORCID: https://orcid.org/0000-0002-7629-6843)
- Isaac Chipako (ORCID: https://orcid.org/0000-0003-3538-9231)
- Victor Muleya (ORCID: https://orcid.org/0000-0003-2315-4953)
- Herald Midzi
- Takafira Mduluza (ORCID: https://orcid.org/0000-0002-5613-5014)
- Masimba Mandeya
- Keith Mujeni
Institutions
- University of Zimbabwe (ZW)
- Lancaster University (GB)
- Midlands State University (ZW)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1371/journal.pntd.0011887
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Merck KGaA