Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials

In randomized clinical trials, CEE-alone increased ovarian cancer incidence and ovarian cancer mortality, while CEE plus MPA did not. By contrast, CEE plus MPA significantly reduced endometrial cancer incidence.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2024-08-22
DOI
https://doi.org/10.1200/jco.23.01918
Citations
16
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
9.32
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article

Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials

Rowan T. Chlebowski, Jean Wactawski‐Wende, Carolyn D. Runowicz, Mihae Song et al.
16 citations
Journal of Clinical Oncology
Endometrial and Cervical Cancer Treatments
9.32
article

Menopausal Hormone Therapy and Ovarian and Endometrial Cancers: Long-Term Follow-Up of the Women's Health Initiative Randomized Trials

Rowan T. Chlebowski, Jean Wactawski‐Wende, Carolyn D. Runowicz, Mihae Song, Aaron K. Aragaki, Andrew M. Kauntiz, Dorothy S. Lane, Holly Ruth Harris, Reina Haque, Kathy Pan, Howard D. Strickler, Thomas E. Rohan
article en
16 citations

Abstract

In randomized clinical trials, CEE-alone increased ovarian cancer incidence and ovarian cancer mortality, while CEE plus MPA did not. By contrast, CEE plus MPA significantly reduced endometrial cancer incidence.

Journal of Clinical OncologyVol. 42(30)
Albert Einstein College of Medicine (US), City Of Hope National Medical Center (US), Kaiser Permanente (US), Florida International University (US), University of Florida (US), Stony Brook School (US), Fred Hutch Cancer Center (US), Stony Brook University (US), University at Buffalo, State University of New York (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 2%
Endometrial and Cervical Cancer Treatments
9.32
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