GOLD-Grade Specific Disease Characterization and Phenotyping of COPD Using Quantitative Computed Tomography in the Nationwide COSYCONET Multicenter Trial in Germany
QCT demonstrates increasing hyperinflation and emphysema depending on the GOLD grade, while airway wall thickening increases until GOLD3 and airway dilatation occur in GOLD4. QCT identifies four disease phenotypes with implications for lung function and prognosis.
Authors
- Mark Oliver Wielpütz (ORCID: https://orcid.org/0000-0001-6962-037X)
- Simon M. F. Triphan (ORCID: https://orcid.org/0000-0003-2068-1184)
- Oliver Weinheimer (ORCID: https://orcid.org/0000-0002-9507-076X)
- Philip Konietzke (ORCID: https://orcid.org/0000-0001-8580-6721)
- Felix Wuennemann (ORCID: https://orcid.org/0000-0002-1904-907X)
- Hans‐Ulrich Kauczor (ORCID: https://orcid.org/0000-0002-6730-9462)
- Rudolf A. Jörres (ORCID: https://orcid.org/0000-0002-9782-1117)
- Sebastian Nauck (ORCID: https://orcid.org/0000-0002-1216-9511)
- Bertram J. Jobst (ORCID: https://orcid.org/0000-0002-3343-2526)
- Claus Franz Vogelmeier (ORCID: https://orcid.org/0000-0002-9798-2527)
- Claus Peter Heußel (ORCID: https://orcid.org/0000-0001-5809-5733)
- Marilisa Konietzke
- Jürgen Biederer
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- German Center for Lung Research (DE)
- Universities of Giessen and Marburg Lung Center (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Latvia (LV)
Publication Details
- Journal
- Respiration
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1159/000540781
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42