Prevalence and Clinical Implications of Autoantibodies in Juvenile Dermatomyositis
MSAs/MAAs were identified in 81% of children with JDM in our study, which is higher than most other studies. The most frequently observed antibodies displayed a pattern consistent with other studies. Anti-TIF1γ was associated with a younger age at onset and disease flares even after attaining a complete clinical response. Anti-NXP2 had higher odds of severe muscular weakness. These observations suggest consistency in certain phenotypic associations observed across geographic boundaries.
Authors
- Narendra Kumar Bagri (ORCID: https://orcid.org/0000-0001-8004-0536)
- Rakesh Lodha (ORCID: https://orcid.org/0000-0003-2608-1163)
- Ashish Datt Upadhyay (ORCID: https://orcid.org/0000-0002-5957-5429)
- B. Dhakal
- Sushil Kumar Kabra (ORCID: https://orcid.org/0000-0002-8890-8261)
- Yogendra Singh (ORCID: https://orcid.org/0000-0002-3902-4355)
- Lata Singh (ORCID: https://orcid.org/0000-0002-8981-2237)
- Sathvik Reddy Erla
- Alen Joe Joseph
Institutions
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- JCR Journal of Clinical Rheumatology
- Published
- 2024-08-22
- DOI
- https://doi.org/10.1097/rhu.0000000000002127
- Citations
- 1
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.39